Supplements with purported effects on muscle mass and strength

PURPOSE: Several supplements are purported to promote muscle hypertrophy and strength gains in healthy subjects, or to prevent muscle wasting in atrophying situations (e.g., ageing or disuse periods). However, their effectiveness remains unclear. METHODS: This review summarizes the available evidence on the beneficial impacts of several popular supplements on muscle mass or strength. RESULTS: Among […]

Athletic “oldest-old”: alive and kicking

On October 13, 2018, an 86-year-old Japanese man named Hiromu Inada, finished the Ironman Triathlon World Championship (Hawaii) in 16 hours 54 minutes. The Ironman triathlon is the paradigm of grueling endurance races, with its 2.4-mile swim, 112-mile cycle, and 26.2-mile marathon all rolled into 1 event held under extreme heat, humidity, and wind conditions. […]

More on the record-breaking performance in a 70-year-old marathoner

To the Editor: Robinson et al.1 (April 11 issue) determined the physiological profile of a 70-year-old man who ran a marathon in 2:54:23, thanks to his ability to “maintain a remarkably high percentage of his maximum oxygen uptake” (approximately 95%, according to our calculations). Although persons 80 years of age reach the ventilatory threshold closer to the […]

Is health status impaired in childhood cancer survivors? a systematic review and meta-analysis

BACKGROUND: An increase in survival rates of childhood cancer is associated with long-term health issues in survivors. METHODS: We conducted a systematic review and meta-analysis comparing health status-related endpoints in childhood cancer survivors (CCS) versus controls. RESULTS: Eighty-six studies (n = 98,480 participants, 62% CCS) were included in the review. Of these, 73 studies (n = 96,550, 63% CCS) […]


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